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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPD1
All Species:
51.52
Human Site:
S187
Identified Species:
75.56
UniProt:
P10809
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10809
NP_002147.2
573
61055
S187
K
E
I
G
N
I
I
S
D
A
M
K
K
V
G
Chimpanzee
Pan troglodytes
XP_001169030
573
61022
S187
K
E
I
G
N
I
I
S
D
A
M
K
K
V
G
Rhesus Macaque
Macaca mulatta
XP_001082397
576
61283
S187
K
E
I
G
N
I
I
S
D
A
I
K
K
V
G
Dog
Lupus familis
XP_536016
573
60977
S187
K
E
I
G
N
I
I
S
D
A
M
K
K
V
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_034607
573
60937
S187
K
D
I
G
N
I
I
S
D
A
M
K
K
V
G
Rat
Rattus norvegicus
P63039
573
60937
S187
K
D
I
G
N
I
I
S
D
A
M
K
K
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL72
573
60954
S187
Q
E
I
G
N
I
I
S
D
A
M
K
K
V
G
Frog
Xenopus laevis
NP_001083970
579
61616
S187
E
E
I
G
K
I
I
S
D
A
M
K
K
V
G
Zebra Danio
Brachydanio rerio
NP_851847
575
61178
S187
T
E
V
G
N
I
I
S
N
A
M
K
K
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02649
573
60790
S183
Q
A
I
G
N
L
I
S
E
A
M
K
K
V
G
Honey Bee
Apis mellifera
XP_392899
570
60394
S182
K
A
I
G
N
L
I
S
D
A
M
K
K
V
G
Nematode Worm
Caenorhab. elegans
P50140
568
60082
S178
T
V
V
G
N
L
I
S
D
A
M
K
K
V
G
Sea Urchin
Strong. purpuratus
XP_795205
586
62222
S193
A
G
I
G
E
L
I
S
R
A
M
K
K
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43298
576
60917
A196
R
E
I
G
E
L
I
A
K
A
M
E
K
V
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29197
577
61262
A193
R
E
I
G
E
L
I
A
K
A
M
E
K
V
G
Baker's Yeast
Sacchar. cerevisiae
P19882
572
60733
A184
S
H
V
G
K
L
L
A
S
A
M
E
K
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
98
N.A.
97.5
97.5
N.A.
N.A.
94
89.4
87.3
N.A.
74
74.6
71
74.9
Protein Similarity:
100
100
98.7
98.9
N.A.
98.2
98.2
N.A.
N.A.
97.7
94.9
94.4
N.A.
86.3
86
82.3
87.3
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
86.6
80
N.A.
73.3
86.6
73.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
93.3
93.3
86.6
73.3
Percent
Protein Identity:
N.A.
58.3
N.A.
57.8
55.6
N.A.
Protein Similarity:
N.A.
76.9
N.A.
76.4
73.3
N.A.
P-Site Identity:
N.A.
60
N.A.
60
40
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
86.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
0
0
0
0
0
19
0
100
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
0
0
63
0
0
0
0
0
0
% D
% Glu:
7
57
0
0
19
0
0
0
7
0
0
19
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
100
0
0
0
0
0
0
0
0
0
0
100
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
82
0
0
57
94
0
0
0
7
0
0
0
0
% I
% Lys:
44
0
0
0
13
0
0
0
13
0
0
82
100
0
0
% K
% Leu:
0
0
0
0
0
44
7
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
94
0
0
0
0
% M
% Asn:
0
0
0
0
69
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
0
0
82
7
0
0
0
0
0
0
% S
% Thr:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
19
0
0
0
0
0
0
0
0
0
0
100
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _